def runJSX (aFilePath ):
    id60 = psApp.stringIDToTypeID ( "AdobeScriptAutomation Scripts" )
    desc12 = comtypes.client.CreateObject('Photoshop.ActionDescriptor')
    id61 = psApp.charIDToTypeID( "jsCt" )
    desc12.putPath( id61, aFilePath )
    id62 = psApp.charIDToTypeID( "jsMs" )
    desc12.putString( id62, "null" )
    psApp.executeAction( id60, desc12, 2 )

psApp = comtypes.client.CreateObject('Photoshop.Application')
runJSX ( "C:\\OpenDocument.jsx" )